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Iron Culture

Ep 354 - All About "Central" or "Systemic" Fatigue

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19 Nov 2025 · 1h 37m

Muscle growthRecovery

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About this episode

In this episode, Eric Trexler and Eric Helms begin by discussing Helms' competition updates and the sad state of affairs in academic publishing (that is, scientific journals). Eric and Eric then take a deep dive into the complexities of central fatigue, systemic fatigue, the accumulation of fatigue, and deloading strategies. The conversation emphasizes the importance of personalized approaches to recovery and the role of intensity in achieving hypertrophy. They close by discussing misconceptions

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