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#582: GLP-1 Agonists: Side Effects, Management and Diet – Dr. Spencer Nadolsky

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28 Oct 2025 · 48 min

Nutrition basicsWeight management

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GLP-1 receptor agonists have emerged as a groundbreaking tool in obesity treatment. In this episode, Dr. Spencer Nadolsky (an obesity specialist) explains how these medications are now yielding unprecedented weight loss outcomes in people with obesity. The discussion centers on GLP-1 agonist drugs like semaglutide and tirzepatide: how they work, how much weight loss they can produce, and why they represent a paradigm shift in obesity management. Importantly, the conversation addresses practical

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