Sigma Nutrition Radio
#610: Rock, Paper, Salmon – Errors in Interpreting Food Substitution Models
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16 Jun 2026 · 57 min
Nutrition basics
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About this episode
When considering the health impact of foods, it is important to consider "compared to what?". Increasing the amount of a certain food or nutrient in the diet, typically implies a displacement of another. While comparisons are more obvious in trials, in epidemiology food substitution models can be useful to help us determine the health effects of increasing/decreasing intake of a food, food group or nutrient. However, these models are often misinterpreted and miscommunicated as if they are a game