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In Episode #159, I sat down with nutrition scientist Alan Flanagan to take a deep dive into the history of the diet-heart hypothesis, with emphasis on the work of Ancel Keys. We discussed the context for researching heart disease after World War II and the motivation for Ancel Keys’s 1958 Seven Countries Study – the world’s first multi-country nutritional epidemiological study. We also covered the North Karelia Project (a Finland-based, long-term project that aimed to reduce cardiovascular...